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Geral 2025
DOI: 10.1016/j.ric.2025.100030

Efficacy and safety of delayed thrombolysis for ischemic stroke within 4.5-24h: A systematic review and meta-analysis of randomized controlled trials

Autores: Jesús Fernando Briceño-Domínguez, Grecia Bejarano-Carabeo, Rodrigo Góes de Oliveira Galvão et al.

The efficacy and safety of thrombolytics within the first 4.5h of ischemic stroke symptom onset are well documented; however, evidence beyond this timeframe remains contentious. To assess the efficacy and safety of delayed thrombolysis (4.5-24-h...

Geral Nov 2025
DOI: 10.1186/s13643-025-02982-1

Effectiveness of inspiratory muscle training and multicomponent physical training in patients with post-COVID conditions: a systematic review and meta-analysis

Autores: Andresa da Costa Correia, Fernanda Ribeiro, Fábio Ferreira Amorim et al.

There is evidence that fatigue and dyspnea are among the most frequently reported symptoms of post-COVID condition. Therefore, several studies have investigated respiratory muscle or global peripheral muscle training as strategies to manage those symptoms....

Geral Jan 2026
DOI: 10.1093/sxmrev/qeag013

Radiofrequency versus vaginal estrogen for menopausal sexual dysfunction: a systematic review and meta-analysis of randomized clinical trials

Autores: Alice F Diniz, Mariana X Ciuffatelli, Laura F Queiroz et al.

Genitourinary syndrome of menopause (GSM) is a prevalent condition among postmenopausal women, often leading to sexual dysfunction and significantly impacting quality of life. While vaginal estrogen is the standard treatment, alternatives are needed for those...

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